Astaxanthin is considered the most powerful natural antioxidant known to science. Antioxidants are vital substances that protect the body from harmful influences. Thanks to its cell-protective properties, astaxanthin can have positive effects on the immune system, the cardiovascular system, the eyes, the skin, brain function, and cellular aging.
Astaxanthin – 100% naturally occurring antioxidant
Astaxanthin belongs to the carotenoid group. As naturally occurring antioxidants, they give many fruits and vegetables their red, yellow, or orange color (Spektrum, 2023). Astaxanthin is a red pigment produced by microalgae such as Haematococcus pluvialis. Haematococcus pluvialis, also known as blood-red algae, is normally green in color. When it experiences stress—such as intense sunlight, a lack of nutrients, or a shortage of water—it produces large amounts of astaxanthin. As a result, it changes color from green to red and is protected from harmful influences. With the help of astaxanthin, it can survive for many weeks without nutrients or water (Windisch, 2021).
Astaxanthin Protects Cells
Astaxanthin is considered one of the most powerful antioxidants found in nature. It is even described as the world’s most powerful antioxidant. Its effectiveness far surpasses that of all other known antioxidants. Studies have shown that it is 6,000 times more potent than vitamin C and 100 times more potent than vitamin E (Nishida, 2007).
Antioxidants protect the body from so-called “free radicals.” These are produced, on the one hand, by various metabolic processes in the body. On the other hand, they are also caused by harmful external factors such as cigarette smoke, UV radiation, environmental toxins, or stress. Free radicals alter cells, can damage genetic material, and contribute to the aging process (DocCheck Flexikon, 2023). When there are too many free radicals in the body, so-called “oxidative stress” occurs. Oxidative stress can cause damage to the body’s cells. It is also thought to play a role in the development of various health problems (DocCheck Flexikon, 2023). Furthermore, it causes the skin to age more quickly (Verbraucherzentrale, 2023). Antioxidants, on the other hand, are true miracle cures; they help the body fight free radicals by trapping them and rendering them harmless. In doing so, they can protect the body’s own cells from premature aging.
Not All Astaxanthin Is Created Equal
In addition to naturally derived astaxanthin from microalgae, there is also synthetically produced astaxanthin. However, studies have shown that natural astaxanthin is far superior to the synthetic version. Its ability to neutralize free radicals is 20 times greater than that of synthetically produced astaxanthin (Capelli, 2013).
Astaxanthin—the All-Around Wonder
Astaxanthin is a true powerhouse with a wide range of health benefits. It is a highly effective cellular protector that supports the skin, eyes, cardiovascular system, immune system, muscles, ligaments, and tendons, as well as the brain and nervous system. These many different health benefits are due to its protective effects against oxidative stress. As a powerful antioxidant, astaxanthin can prevent oxidative stress in the body (Donoso, 2021) and thus influence a wide variety of bodily functions.
1. Astaxanthin Protects the Skin
As the body’s outer protective barrier, the skin is constantly exposed to environmental factors such as UV radiation, heat, cold, environmental toxins, and much more. As a result, it must cope with particularly high levels of free radicals and oxidative stress. This damages the cells and causes the skin to age. Thanks to its antioxidant properties, astaxanthin can protect the skin from UV-induced damage (Ito, 2018; Donoso, 2021). It also improves the skin’s moisture content and elasticity (Ito, 2018; Zhou, 2021; Tominaga, 2012; Yamashita, 2006; Phetcharat, 2015). Clinical studies have shown that astaxanthin can demonstrably reduce wrinkle depth (Tominaga, 2012; Yamashita, 2006; Tominaga, 2017; Zhou, 2021; Phetcharat, 2015) and protects the skin from aging processes (Zhou, 2021).
2. Astaxanthin Supports the Immune System
Astaxanthin has a positive effect on the immune system. It supports the immune system by increasing the number and activity of various immune cells. At the same time, it is able to reduce oxidative stress in the body (Park, 2010; Baralic, 2015).
3. Astaxanthin—for Muscles, Tendons, Ligaments, and Joints
During physical activity, lactate levels in the muscles can rise, which can cause fatigue and a burning sensation in the muscles. Astaxanthin can lower lactate levels and thus support muscle function (Sawaki, 2002; Wu, 2019).
Astaxanthin protects against the formation of free radicals during exercise and can thereby reduce muscle damage (Wu, 2019; Djordjevic, 2012). It can also improve muscular endurance, strength (Malmsten, 2009), flexibility (Baralic, 2015), and recovery after exercise.
Even symptoms caused by overexertion during exercise can improve more quickly with astaxanthin. For example, one study showed that symptoms of tennis elbow improved more quickly after taking astaxanthin (Spiller, 2006).
There is also preliminary promising evidence from animal studies suggesting that astaxanthin has a positive effect on the joints (Sun, 2019; Kumar, 2020; Park, 2020).
4. Astaxanthin Supports Cardiovascular Health
Astaxanthin protects the heart in various ways: It is capable of lowering blood lipid levels. It also reduces “bad” cholesterol (LDL) and increases “good” cholesterol (HDL) in the blood (Yoshida, 2010). Studies also suggest that astaxanthin can help lower blood pressure (Mashhadi, 2018).
5. Astaxanthin helps maintain vision
Recent research suggests that oxidative stress also plays a role in the development of vision problems (Donoso, 2021). Clinical studies show that astaxanthin improves blood circulation in the eye and is therefore important for maintaining vision (Donoso, 2021; Nagaki, 2005; Saito, 2012). In addition, astaxanthin can improve accommodation—that is, the eye’s ability to switch between near and far focus—(Nagaki, 2002) and help prevent eye fatigue (Sawaki, 2002).
6. Astaxanthin—Good for the Brain
There is evidence suggesting that astaxanthin may be important for maintaining and supporting brain function. In one study, astaxanthin improved memory performance in individuals who complained of forgetfulness (Katagiri, 2012). In another study, astaxanthin was shown to reduce the amount of toxins in the brain (Nakagawa, 2011).
Astaxanthin—the Power Nutrient
- protects the skin
- supports the immune system
- for muscles, tendons, ligaments, and joints
- supports cardiovascular health
- helps maintain vision
- good for the brain
Sources
- Spektrum. Encyclopedia of Biology. Carotenoids. Retrieved January 26, 2023, from spektrum.de
- Windisch, J. Growth of Various H. pluvialis Strains in Different Culture Media and Development of a New Analytical Method for Determining Astaxanthin Content. Bachelor’s thesis, 2021. Retrieved January 30, 2023, from zhaw.ch
- Nishida Y, Yamashita E, Miki W. Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using a chemiluminescence detection system. Carotenoid Science. 2007;11:16–20. researchgate.net
- DocCheck Flexikon. Oxidative stress. Retrieved January 31, 2023, from doccheck.com
- Consumer Center. Antioxidants: Helpers against free radicals. Retrieved January 30, 2023, from verbraucherzentrale.de
- Capelli B, Bagchi D, Cysewski G. Synthetic astaxanthin is significantly inferior to algal-based astaxanthin as an antioxidant and may not be suitable as a human nutritional supplement. NutraFoods. 2013;12:145–52. link.springer.com
- Donoso A, González-Durán J, Muñoz AA, González PA, Agurto-Muñoz C. Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials. Pharmacol Res. 2021;166:105479. pubmed.ncbi.nlm.nih.gov
- Ito N, Seki S, Ueda F. The protective role of astaxanthin against UV-induced skin damage in healthy individuals—a randomized, double-blind, placebo-controlled trial. Nutrients. 2018;10(7):817. pubmed.ncbi.nlm.nih.gov
- Zhou X, Cao Q, Orfila C, Zhao J, Zhang L. Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Aging. Nutrients. 2021;13(9):2917. pubmed.ncbi.nlm.nih.gov
- Tominaga K, Hongo N, Karato M, Yamashita E. Cosmetic benefits of astaxanthin in human subjects. Acta Biochim Pol. 2012;59(1):43-47. pubmed.ncbi.nlm.nih.gov
- Yamashita E. The effects of a dietary supplement containing astaxanthin on skin condition. Food Style. 2006;9:72. semanticscholar.org
- Phetcharat L, Wongsuphasawat K, Winther K. The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity. Clin Interv Aging. 2015;10:1849-1856. pubmed.ncbi.nlm.nih.gov
- Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi Y. Protective effects of astaxanthin on skin deterioration. J Clin Biochem Nutr. 2017;61:33–39. pubmed.ncbi.nlm.nih.gov
- Park JS, Chyun JH, Kim YK, Line LL, Chew BP. Astaxanthin reduced oxidative stress and inflammation and enhanced the immune response in humans. Nutr Metab (Lond). 2010;7:18. pubmed.ncbi.nlm.nih.gov
- Baralic I, Andjelkovic M, Djordjevic B, et al. Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. Evid Based Complement Alternat Med. 2015;2015:783761. pubmed.ncbi.nlm.nih.gov
- Sawaki K, et al. Sports performance benefits from taking natural astaxanthin, as evidenced by improvements in visual acuity and reduced muscle fatigue in humans. Journal of Clinical Therapeutics & Medicines. 2002;18(9):73-88. semanticscholar.org
- Wu L, Sun Z, Chen A, Guo X, Wang J. Effect of astaxanthin and exercise on the human body’s antioxidant capacity and on blood lactic acid and blood uric acid metabolism. Sci Sport. 2019;34(5):348–352. sciencedirect.com
- Djordjevic B, Baralic I, Kotur-Stevuljevic J, et al. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. J Sports Med Phys Fitness. 2012;52(4):382–392. pubmed.ncbi.nlm.nih.gov
- Malmsten CL, Lignell A. Dietary supplementation with astaxanthin-rich algal meal improves strength endurance—a double-blind, placebo-controlled study on male students. Carotenoid Sci. 2009;13:20–22.
- Spiller G, et al. Effect of daily use of natural astaxanthin on symptoms associated with tennis elbow (lateral humeral epicondylitis). 2006. Unpublished.
- Sun K, Luo J, Jing X, et al. Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis. Aging (Albany, NY). 2019;11(22):10513–10531. pubmed.ncbi.nlm.nih.gov
- Kumar A, Dhaliwal N, Dhaliwal J, Dharavath RN, Chopra K. Astaxanthin attenuates oxidative stress and inflammatory responses in complete Freund’s adjuvant-induced arthritis in rats. Pharmacol Rep. 2020;72(1):104–114. pubmed.ncbi.nlm.nih.gov
- Mashhadi NS, Zakerkish M, Mohammadiasl J, Zarei M, Mohammadshahi M, Haghighizadeh MH. Astaxanthin improves glucose metabolism and reduces blood pressure in patients with type 2 diabetes mellitus. Asia Pac J Clin Nutr. 2018;27(2):341-346. pubmed.ncbi.nlm.nih.gov
- Yoshida H, Yanai H, Ito K, et al. Administration of natural astaxanthin increases serum HDL cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis. 2010;209:520–523. pubmed.ncbi.nlm.nih.gov
- Nagaki Y, Hayasaka S, Yamajda T, Hayasaka Y, Sanada M, Uonomi T. Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. J Trad Med. 2002;19. semanticscholar.org
- Nagaki Y, Mihara M, Takahashi J, et al. The effect of astaxanthin on retinal capillary blood flow in normal volunteers. Transl J Clin Ther Med. 2005;21(5). semanticscholar.org
- Saito M, Yoshida K, Saito W, et al. Astaxanthin increases choroidal blood flow velocity. Graefe’s Arch Clin Exp Ophthalmol. 2012;250(2):239–245. pubmed.ncbi.nlm.nih.gov
- Katagiri M, Satoh A, Tsuji S, Shirasawa T. Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomized, double-blind, placebo-controlled study. J Clin Biochem Nutr. 2012;51(2):102–107. pubmed.ncbi.nlm.nih.gov
- Nakagawa K, Kiko T, Miyazawa T, et al. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Br J Nutr. 2011;105(11):1563-1571. pubmed.ncbi.nlm.nih.gov
Jutta Hannemann
I am a freelance medical writer and count various companies in the healthcare industry among my clients. After completing my studies in food science at the Technical University of Munich, I initially worked in the food industry for over 10 years before taking the leap into self-employment in 2010. This allows me to perfectly combine my interest in scientific concepts with my passion for scientific writing. My work focuses on all topics related to nutrition, health, and well-being.







